![]() ![]() Enhancing the musicality of protein mapping Protein-to-music algorithms can thus map the structural and physiochemical features of a string of amino acids onto the musical features of a string of notes. Likewise, music consists of sound waves of higher and lower pitches, with changing tempos and repeating motifs. Protein chains can also fold into wavy and curved patterns with ups, downs, turns and loops. LadyofHats/Wikimedia CommonsĪ protein chain can be represented as a string of these alphabetic letters, very much like a string of music notes in alphabetical notation. Aspects of potein structure can be analogous to musical notation. These chains are composed of small units of 20 possible amino acids, each labeled by a letter of the alphabet. Proteins are structured like folded chains. So we led a team of high school students and other scholars to figure out how to create classical music from proteins. While creating music based on proteins isn’t new, different musical styles and composition algorithms had yet to be explored. We’re computational biologists who believe that hearing the sound of life at the molecular level could help inspire people to learn more about biology and the computational sciences. ![]() These analogies can be used not only to help advance research, but also to make the complexity of proteins accessible to the public. There are many surprising analogies between proteins, the basic building blocks of life, and musical notation. With the right computer program, proteins become pleasant music. ![]()
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